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. 2021 Feb 2;11:2771. doi: 10.1038/s41598-021-82156-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Tissue-to-tissue co-expression network of the bovine fetal organ transcriptome. (A) Heat map of 553 tissue-specific genes from the liver, muscle, and cerebrum tissues. (B) Co-expression network of 992 significantly co-expressed genes. Only nodes with a correlation greater than |0.9| are shown. Overlapped genes between analysis were colored based on the tissue with its maximum expression. Transcription factors are represented by a diamond shape. Nodes with few connections not linked to the main network are not showed. Heat map was constructed using pheatmap v.1.010.⁹³ on R⁷⁹, whereas gene network was created on Cytoscape v.3.7⁸⁹.