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. 2021 Feb 2;11:2771. doi: 10.1038/s41598-021-82156-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Cerebrum regulatory network of differentially co-expressed genes from the bovine transcriptome. Nodes are genes with significant changes in the correlation between control and nutrient restricted fetus (q ≤ 0.05). The node size and color (from light to dark) are proportional to the number of connections for each gene. Nodes with few connections not linked to the main network are not showed. Only those gene pairs assigned as DEG, TS, or TF are shown. Transcription factors are represented by a diamond shape. Differentially expressed genes are labeled in blue. Edges are colored based on the differential correlation class (+/− , red; + /0, salmon; − /+ , green; − /− , deep sky blue; − /0, green-yellow; 0/+ , magenta; 0/− , brown). Gene network was created on Cytoscape v.3.7⁸⁹.