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. 2021 Feb 2;11:2792. doi: 10.1038/s41598-021-82502-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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(a) Evolution of the serum NTX concentration after administration of a single dose of denosumab and comparison with Marathe’s work³³ and with experiments³⁶; (b) evolution of the plasma concentration after administration of a single dose of denosumab and comparison with Marathe’s work³³ and with experiments³⁶; (c) changes in the concentration of urine CTX from the baseline after administration of a single dose of Ibandronate and comparison with Marathe’s work⁸ and with experiments³⁵.