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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Paediatr Perinat Epidemiol. 2020 Sep 24;35(1):143–152. doi: 10.1111/ppe.12692

Table 3.

Comparison of intercourse averaging weekly, every other day, and daily on simulated time to pregnancy and fecundability odds ratiosa over 12 cycles of follow-up in a cohort of 100,000 womenb (using Scenario 1c relationship between sex and implantation)

Weekly Every other day Daily
Cycle Population at risk % becoming pregnant Cumulative pregnancy rate (%) Population at risk % becoming pregnant Cumulative pregnancy rate (%) FORd Population at risk % becoming pregnant Cumulative pregnancy rate (%) FORd
1 100,000 15.1 15.1 100,000 33.5 33.5 2.83 100,000 37.1 37.1 3.32
2 84,900 12.7 25.9 66,544 28.6 52.5 3.16 62,873 31.8 57.1 3.80
3 74,083 10.9 34.0 47,526 23.9 63.8 3.42 42,900 26.6 68.5 4.22
4 66,000 9.3 40.1 36,190 20.7 71.3 3.71 31,499 23.1 75.8 4.67
5 59,868 7.9 44.9 28,699 17.9 76.4 3.98 24,222 20.1 80.6 5.12
6 55,132 6.9 48.7 23,572 15.2 80.0 4.22 19,364 17.0 83.9 5.51
7 51,335 5.8 51.7 19,982 13.2 82.7 4.46 16,070 14.7 86.3 5.89
8 48,352 4.9 54.0 17,343 10.9 84.6 4.66 13,713 12.2 88.0 6.22
9 45,974 4.3 56.0 15,455 9.7 86.0 4.84 12,035 10.7 89.3 6.52
10 44,004 3.6 57.6 13,963 8.0 87.2 5.00 10,749 8.8 90.2 6.78
11 42,401 3.0 58.9 12,842 6.7 88.0 5.14 9,799 7.4 90.9 7.01
12 41,141 2.6 59.9 11,977 6.3 88.8 5.28 9,069 7.2 91.6 7.28
a

Fecundability odds ratios for every other day and daily calculated relative to weekly intercourse

b

Anovulation set equal to 8% for each cycle of observation; probability of implantation|fertilization = 70% and probability of fertilization|sex & ovulation = 59% for the first cycle of observation, followed by a 7.5% reduction per cycle for implantation|fertilization and fertilization|sex & ovulation; probability of implantation calculated using Equation 1.

c

Scenario 1: among fecund couples attempting conception, the maximum probability of attaining pregnancy is ~38% when sexual intercourse always occurs in the fertile window (sex = 1.0)15.

d

Fecundability Odds Ratio