Table 1.
Demographic and Clinical Variables for High-Risk and Healthy Comparison Youth
| Group Analysis | Healthy Comparison (HC) (N=30) | High Risk (HR) (N=34) | Statistics | ||||
|---|---|---|---|---|---|---|---|
| Site (Stanford/UCLA) | 21/9 | 17/17 | χ2(1)=2.64; p=.10 | ||||
| Age (SD) | 14.41 (2.27) | 13.98 (2.64) | t(62)=.70; p=.48 | ||||
| Sex (F/M) | 16/14 | 19/15 | χ2(1)=0.04; p=.84 | ||||
| Motion: absolute mean displacement (mm) (mean, SD, range) | .22 (.34), [.04–1.95] | .33 (.29), [.07–1.17] | t(62)=1.37; p=.18 | ||||
| Treatment Group Analysis | HR FFT-HR (n=16) | HR EC (n=18) | Statistics | ||||
| pre | post | pre | post | Pre | post | ||
| Site (Stanford/UCLA) | 7/9 | -- | 10/8 | -- | χ2(1)=0.47; p=.49 | -- | |
| Age (SD) | 14.57 (2.39) | 15.02 (2.37) | 13.45 (2.80) | 13.84 (2.79) | t(32)=1.24; p=.22 | t(32)=1.30; p=.20 | |
| Sex (F/M) | 8/8 | -- | 7/11 | -- | χ2(1)=0.42; p=.52 | -- | |
| Motion: absolute mean displacement (mm) (mean, SD, range) | .31 (.25), [.07–.77] | .36 (.29), [.10–1.22] | .35 (.33), [.08–1.17] | .30 (.33), [.07–1.17] | t(32)=−.33; p=.74 | t(32)=.50 p=.62 | |
| CDRS-R mean (SD) | 46.87 (10.31) | 39.56 (13.07) | 50.67 (17.67) | 36.83 (15.99) | t(32)=−.75; p=.46 | t(32)=.54; p=.59 | |
| YMRS mean (SD) | 10.00 (7.73) | 8.25 (6.12) | 11.78 (6.23) | 9.28 (5.54) | t(32)=−.74; p=.46 | t(32)=−.51; p=.61 | |
| Primary Diagnosis | |||||||
| MDD | 11 (69%) | 9 (50%) | χ2(1)=1.23; | ||||
| BD-NOS | 5 (31%) | 9 (50%) | p=.27 | ||||
| Medications at Baseline | |||||||
| Unmedicated | 4 (25%) | 10 (55%) | χ2(1)=3.26; p=.07 | ||||
| Antidepressant | 8 (50%) | 2 (11%) | χ2(1)=6.17; p=.01 | ||||
| Antipsychotic | 3 (19%) | 7 (39%) | χ2(1)=2.06; p=.36 | ||||
| Anticonvulsant | 4 (25%) | 2 (11%) | χ2(1)=1.12; p=.29 | ||||
| Anxiolytic | 0 (0%) | 1 (6%) | χ2(1)=.92; p=.34 | ||||
| Stimulant | 4 (25%) | 4 (22%) | χ2(1)=.04; p=.85 | ||||
Note: BD-NOS =Bipolar Disorder, Not Otherwise Specified; CDRS-R = Children’s Depression Rating Scale-Revised; EC = Enhanced Care; FFT-HR = Family Focused Therapy for High-Risk Youth; MDD = Major Depressive Disorder; YMRS = Youth Mania Rating Scale; values indicate mean ± SD = standard deviation.