Table 2:
Predictors of detection of high grade dysplasia or esophageal adenocarcinoma on initial surveillance endoscopy
| Univariate OR (95% CI) | P-Value | Multivariate OR (95% CI) |
P-Value | |
|---|---|---|---|---|
| Gender | ||||
| Female | REF | REF | ||
| Male | 4 (1.6-10.1) | 0.0011 | 4.8 (1.58-14.74) | 0.0056 |
| Age | ||||
| 1-Year Increments | 1.05 (1.03-1.08) | <.0001 | 1.05 (1.02-1.09) | 0.0001 |
| Smoking | ||||
| None | REF | REF | ||
| Current | 2.6 (1-6.4) | 0.0369 | 2.68 (0.89-8.02) | 0.0780 |
| Past | 2.26 (1.1-4.6) | 0.0247 | 1.97 (0.72-5.34) | 0.1843 |
| Provider | ||||
| Non-Gastroenterologists | REF | REF | ||
| Gastroenterologists | 3.6 (1.3-10) | 0.0154 | 2.49 (0.84-7.31) | 0.0971 |
| Barrett’s Length | ||||
| 1 CM Increments | 1.18 (1.09-1.26) | <.0001 | 1.12 (1.02-1.21) | 0.0116 |
| Time Period | ||||
| 1991-2000 | REF | REF | ||
| 2001-2010 | 8.16 (1.09-60.8) | 0.0405 | 8.57 (0.91-66.80) | 0.0601 |
| 2011-2019 | 9.48 (1.28-70.3) | 0.0277 | 7.89 (0.75-62.676) | 0.0926 |
| Visible Abnormality on Endoscopy | ||||
| Absent | REF | REF | ||
| Present | 15.61 (8.11-30.05) | <.0001 | 8.45 (3.69-19.34) | <.0001 |
| Reflux | ||||
| Absent | REF | |||
| Present | 1.03 (0.59-1.8) | 0.89 | ||
| Dysphagia | ||||
| Absent | REF | |||
| Present | 1.14 (0.54-2.3) | 0.72 | ||
| Iron Deficiency Anemia | ||||
| Absent | REF | |||
| Present | 3.3 (1.8-6.1) | <.0001 | ||
| Dyspepsia | ||||
| Absent | REF | |||
| Present | 0.19 (0.04-0.81) | 0.0247 | ||
| Hiatal Hernia | ||||
| Absent | REF | |||
| Present | 1.19 (0.66-2.1) | 0.54 | ||
| BE Length/Bottle ratio* | ||||
| Inadequate Biopsy | REF | |||
| Adequate Biopsy | 0.54 (0.42-1.3) | 0.1141 |
*
Patients who had targeted biopsy were excluded from the analysis.