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Characterization of ADAM10- and ADAM17-expressing cells in proliferative vitreoretinopathy epiretinal fibrocellular membranes. ADAM10 (A) and ADAM17 (B) immunoreactivities were detected in spindle-shaped myofibroblasts. Double immunohistochemistry for CD45 (brown) and ADAM10 (red) (C) or ADAM17 (D) demonstrated co-expression in leukocytes (arrows). No counterstain to visualize the cell nuclei was applied in panels (C, D) (scale bar, 10 μm).
