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. 2020 Jul 20;26(3):e12942. doi: 10.1111/adb.12942

FIGURE 6.

FIGURE 6

MORflox‐vGluT2cre mice have altered oxycodone withdrawal‐related behaviors. (A) Schematic of experiment schedule. (B) Global withdrawal scores for mice following a saline injection and 1.5 h later, a naloxone injection [(n = 16(8M/8F) Cre+ (KO),13(5M/8F) Cre− (Ctrl)]. Cre+ (KO) mice had a higher global withdrawal score following saline injection than Cre− (Ctrl) mice but had a lower global withdrawal score following naloxone injection than Cre− (Ctrl) mice. Data are collapsed across sex. Data for individual withdrawal‐related behaviors are presented in Figure S7. *p < 0.05; **p < 0.01; ***p < 0.001. Error bars indicate ± SEM. Cre+ (KO) = MORflox‐vGluT2cre positive (+); Cre– (Ctrl) = MORflox‐vGluT2cre negative (−)