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Schematic figure. POMC neurons in the hypothalamic arcuate nucleus activate secondary neurons in the paraventricular nucleus (PVN) and inhibit the neurons in the lateral hypothalamic area (LHA), resulting in a reduction in food intake and increasing energy expenditure. In contrast, in the resistance leptin context, NPY increases food intake and reduces energy expenditure. In this study, exercise increased the PI3k subunit and POMC levels and decreased food intake
