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. 2021 Feb 2;8:3. doi: 10.1186/s40580-021-00253-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Albumin release by liver MPS in control and fibrotic condition for 144 h. A sudden decrease in albumin concentration was noted after applying a fibrosis stimulus (TGF-β1) at 72 h (data presented as mean ± SD, bar column with cross lines representing the control values). b Urea production by liver MPS in control and fibrotic condition for 144 h. TGF-β1 stimulation for fibrosis induction at 72 h reduced the urea release by the hepatocytes [data presented as mean ± standard deviation (SD) bar column without cross lines representing the control values]