. Author manuscript; available in PMC: 2022 Jun 1.

Published in final edited form as: Brain Imaging Behav. 2021 Jun;15(3):1364–1373. doi: 10.1007/s11682-020-00335-1

Table 3.

Endogenous and net oxidative DNA damage as per Comet assay by case-control group and timepoint

	Endogenous DNA damage			Oxidative DNA damage

	TM Mean (SD)		TM_FPG-net Mean (SD)		TM_EndoIII-net Mean (SD)
	Baseline	Follow-up	Baseline	Follow-up	Baseline	Follow-up

Controls (n=12)	1.26 (0.45)	1.05 (0.55)	7.88 (4.18)	7.12 (3.45)	0.92 (0.98)	0.84 (0.75)
Cases (n=13)	1.22 (1)	1.22 (1.01)	9.36 (2.68)	9 (5.83)	1.27 (1.29)	2.03 (2.13)^†
	TI Mean (SD)		TI_FPG-net Mean (SD)		TI_EndoIII-net Mean (SD)

	Baseline	Follow-up	Baseline	Follow-up	Baseline	Follow-up

Controls (n=12)	9.14 (1.98)	8.04 (1.87)	21.81 (9.5)	20.58 (8.63)	4.37 (3.58)	4.22 (3.3)
Cases (n=13)	8.77 (3.44)	8.69 (3.86)	27.11 (7)	26.09 (10.87)	6.61 (5.08)	9.15 (6.73)^*^†

TM and TI, Tail moment and Tail intensity, mean values expressed in arbitrary units; TM_Endo-net and TI_Endo-net, net oxidative DNA damage measured after EndoIII treatment; TM_FPG-net and TI_FPG-net, net oxidative DNA damage after FpG treatment.

p < 0.05 between group significance;

^†

p < 0.05 within group significance.