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Antibacterial Activities Against Recombinant E. coli Strains Expressing Single Resistance Determinants in an Isogenic Background (MIC, mg/L)
| Resistance Determinant | wt parental | AAC(3)-IV | AAC(3)-II | APH(3’)-Ia | APH(3’)-IIa | APH(3’)-IIb | APH(3’)-VI | armA | rmtB |
|---|---|---|---|---|---|---|---|---|---|
| Strain | EC026 | EC118 | EC200 | EC122 | EC123 | EC125 | EC141 | EC102 | EC103 |
| Apramycin | 2 | 128 | 2–4 | 1–2 | 1 | 1 | 1 | 1 | 1 |
| 2 | 0.5–1 | 4 | 0.5–1 | 2–4 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 |
| 3 | 0.5–1 | 8–16 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5–1 |
| 4 | 0.25–0.5 | 2 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.5 | 0.5 |
