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. Author manuscript; available in PMC: 2022 Jan 19.
Published in final edited form as: ChemMedChem. 2020 Oct 23;16(2):335–339. doi: 10.1002/cmdc.202000726

Table 4.

Antibacterial Activities (MIC, mg/L) Against E. coli Strains with Acquired AAC(3) and APH(3’) Resistancea

Resistance Determinant wt AAC(3)-II AAC(3)-IV APH(3’)-I APH(3’)-II
Strain AG001 AG170 AG173 AG163 AG166
Apramycin 4 4–8 256 4 4–8
Lividomycin B 4–8 4–8 16 >256 4–8
2 2 2 4 4–8 2
3 2 2 16 2–4 2–4
4 1–2 1–2 4 1–2 1–2