Table 1.
Sarcopenia N=72 | No Sarcopenia N=70 | P value | |
---|---|---|---|
Median Age at Transplant (range) | 63.3 (38.2–78.6) | 59.7 (43.8–78.7) | 0.7 |
Male (%) | 46 (63.9%) | 46 (65.7%) | 0.8 |
Race (White) (%) | 63 (87.5%) | 59 (84.3%) | 0.6 |
Median BMI at Transplant (range) | 29.0 (21.5–46.1) | 28.8 (17.8–40.8) | 0.1 |
Time from Diagnosis to Transplant | 5.4 (0.7–30.2) | 5.4 (3.3–27.6) | 0.6 |
Stage (ISS) | 0.5 | ||
ISS-I | 25 (36.8%) | 22 (33.3%) | |
ISS-II | 27 (39.7%) | 25 (37.9%) | |
ISS-III | 16 (23.5%) | 19 (28.8%) | |
Bone Lesions | 63 (87.5%) | 56 (80.0%) | 0.2 |
Median HCT-CI | 1.0 (0.0–8.0) | 1.0 (0.0–7.0) | 0.7 |
KPS | 48 (66.7%) | 44 (62.9%) | 0.6 |
≥90 | |||
Lines of Induction | 0.2 | ||
1 | 59 (81.9%) | 63 (90.0%) | |
2 | 13 (18.1%) | 7 (10.0%) | |
Pre-transplant disease status | 0.3 | ||
≥VGPR | 44 (61.1%) | 37 (52.9%) | |
≤PR | 28(38.9%) | 33 (47.1%) | |
Melphalan dose | 0.6 | ||
140 mg/m2 | 9 (12.5%) | 11 (15.7%) | |
200 mg/m2 | 63 (87.5%) | 59 (84.3%) | |
Outpatient Transplant | 21 (29.2%) | 18 (25.7%) | 0.6 |
Day 100 complications | |||
Any Complication | 24 (33.3.%) | 15 (21.4%) | 0.3 |
Any Adverse Event* | 14 (19.4%) | 8 (11.4%) | 0.2 |
ICU Transfer | 3 (3.5%) | 2 (2.9%) | 0.7 |
Cardiovascular Event | 9 (12.5%) | 2 (2.9%) | 0.03 |
Renal Failure | 2 (2.9%) | 0 (0.0%) | 0.2 |
Respiratory Failure | 0 (0.0%) | 0 (0.0%) | NA |
Sepsis | 6 (8.3%) | 7 (10.0%) | 0.7 |
Unplanned hospitalization | 17 (23.6%) | 11 (15.7%) | 0.2 |
Total days spent in hospital | 12.0 (0.0–40.0) | 12.0 (0.0–43.0) | 0.8 |
Discharge to rehab facility | 3 (4.2) | 4 (5.7) | 0.7 |
Median f/u as survivors (months) | 27.2 (12.4–71.3) | 33.0 (12.8–74.3) | 0.09 |
Any adverse event describes any patient experiencing cardiovascular event, renal failure, respiratory failure, sepsis, or ICU transfer. If one patient experienced more than one adverse event, it is reported as one adverse event by this definition.
Similarly, any complication (CV, renal, respiratory, sepsis, ICU transfer, unplanned hospitalization) is reported as complication per patient. If one patient experienced more than one complication, it is reported as one in this category.