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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: J Immunol. 2020 Nov 23;206(1):132–140. doi: 10.4049/jimmunol.2000870

Figure 2.

Figure 2.

Loss of IL-12Rβ2 signaling has major effects on iNKT cell activation during acute MCMV infection. (A) Frequency and (B) absolute number of iNKT cells (TCRβ+CD1dtet+) from the spleen and liver of IL-12Rβ2 control (black) and IL-12Rβ2 cKO (open) mice at 36 hours post-infection with MCMV. (C) Frequency and (D) representative flow cytometry of IFN-γ+ iNKT cells (TCRβ+CD1dtet+) and (E) frequency of IFN-γ+ NK cells (TCRβ−NK1.1+) from the spleen and liver of indicated mice at 36 hours post-MCMV. Data are pooled from or representative of two (A-E, n=6–8) independent experiments and error bars indicate SEM.