Figure 7. TRIM-NHL proteins control nucleolar size in Drosophila and C. elegans.
A. Drosophila Brat and Mei-P26 repress myc expression, which controls expression of rRNA and ribosome biogenesis factors to affect nucleolar size, particularly wing imaginal discs.
B. C. elegans NCL-1 represses the FIB-1 mRNA to control nucleolar size.