Table 2.
| Trends 1999–2017 |
||||||||
|---|---|---|---|---|---|---|---|---|
| Trend 1 |
Trend 2 |
Trend 3 |
||||||
| Age (years) | Histology1 | Years | APC (95% CI) | Years | APC (95% CI) | Years | APC (95% CI) | AAPC (95% CI) 1999–2017 |
| Total | 1999–2012 | −4.2 (−5.9, −0.4) | 2012–2017 | −17.4† (−30.6, −13.2) | -- | -- | −8.0† (−12.0, −4.7) | |
| 15–203 | SCC | 1999–2010 | −5.6 (−10.3, 6.3) | 2010–2017 | −22.5† (−45.2, −13.2) | -- | -- | −12.7† (−19.5, −8.8) |
| AC | 1999–2006 | 6.0 (−1.1, 25.2) | 2006–2017 | −9.4† (−19.7, −6.7) | -- | -- | −4.1† (−7.8, −7.8) | |
| Total | 1999–2012 | −3.1 (−4.2, 1.4) | 2012–2017 | −9.9† (−25.4, −5.2) | -- | -- | −5.0† (−6.8, −3.7) | |
| 21–24 | SCC | 1999–2012 | −3.1 (−4.3, 1.6) | 2012–2017 | −11.2† (−29.2, −5.7) | -- | -- | −5.5† (−7.7, −3.9) |
| AC | 1999–2017 | −3.6† (−5.9, −1.5) | -- | -- | -- | -- | −3.6† (−5.9, −1.5) | |
| Total | 1999–2012 | −3.0 (−6.6, 4.1) | 2012–2015 | 5.7 (−7.8, 9.4) | 2015–2017 | −9.1 (−18.0, 2.2) | −2.3† (−3.3, −1.0) | |
| 25–29 | SCC | 1999–2012 | −3.6 (−7.2, 4.8) | 2012–2015 | 7.9 (−9.5, 12.3) | 2015–2017 | −8.4 (−18.5, 4.3) | −2.3† (−3.4, −1.0) |
| AC | 1999–2017 | −1.6† (−2.8, −0.4) | -- | -- | -- | -- | −1.6† (−2.8, −0.4) | |
Data Sources: Center for Disease Control and Prevention’s National Program of Cancer Registries and the National Cancer Institute’s Surveillance, Epidemiology, and End Results Program.
Abbreviations: SCC = squamous cell carcinoma, AC = adenocarcinoma, APC = annual percent change, AAPC = average annual percent change
Cervical cancers (International Classification of Diseases for Oncology, Third Edition [ICD-O-3] site codes C53.0–C53.9) are limited to carcinomas (ICD-O-3 histology codes 8010–8671, 8940–8941); SCC includes ICD-O-3 codes 8050–8084,8120–8131; AC includes ICD-O-3 codes 8140–8575
Cancer incidence compiled from cancer registries that meet the data quality criteria for all invasive cancer sites combined for each year during the period 1999–2017 (covering 97.8% of the U.S. population).
Year of diagnosis in women ages 15–20 is grouped into 2-year intervals during the years 1999–2014, and one 3-year interval (2015–2017) due to sparse data
Significant at p<0.05. Trends were measured with AAPC in rates and were considered to increase or decrease if p<0.05; otherwise rates were considered stable.