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. Author manuscript; available in PMC: 2021 Feb 3.

Published in final edited form as: Pathology. 2020 Sep 20;53(2):205–213. doi: 10.1016/j.pathol.2020.07.006

Table 3.

Association of Annexin A2 and ERG with grade group

	All		p value	CA		p value	AA		p value
	GG 1–2^a	GG 4–5^b	p value	GG 1–2^a	GG 4–5^b	p value	GG 1–2^a	GG 4–5^b	p value
ANXA2			0.0037			0.0272			0.0562
ANXA2(−)	43 (69.4)	49 (46.2)		22 (71.0)	28 (46.7)		21 (67.7)	21 (45.6)
ANXA2(+)	19 (30.6)	57 (53.8)		9 (29.0)	32 (53.3)		10 (32.3)	25 (54.4)
ERG			0.0018			0.0004			0.1841
ERG(−)	25 (40.3)	69 (65.1)		5 (16.1)	33 (55.0)		20 (64.5)	36 (78.3)
ERG(+)	37 (59.7)	37 (34.9)		26 (83.9)	27 (45.0)		11 (35.5)	10 (21.7)
ANXA2/ERG			0.0036			0.0028^c			0.2037^c
ANXA2(−)/ERG(−)	13 (21.0)	24 (22.6)		2 (6.4)	10 (16.7)		11 (35.5)	14 (30.4)
ANXA2(+)/ERG(−)	12 (19.4)	45 (42.4)		3 (9.7)	23 (38.3)		9 (19.0)	22 (47.8)
ANXA2(−)/ERG(+)	30 (48.4)	25 (23.6)		20 (64.5)	18 (30.0)		10 (32.3)	7 (15.2)
ANXA2(+)/ERG(+)	7 (11.3)	12 (11.3)		6 (19.4)	9 (15.0)		1 (3.2)	3 (6.5)

AA, African American; CA, Caucasian American; GG, grade group.

Bold p values are significant.

^a

(Gleason score ≤6 and 3+4).

^b

(Gleason score 8 and 9–10).

^c

Fisher’s exact test.