Table 2.
Treatments and outcomes of patients with tandem lesions versus isolated intracranial large vessel occlusions. Count (percent) reported unless noted otherwise. N=60 unless otherwise specified. Abbreviations: LKW last known well, IQR interquartile range, ICA internal carotid artery, TICI Thrombolysis in Cerebral Infarction score, ICH intracerebral hemorrhage, mRS modified Rankin scale score.
| Tandem Lesion (N=60) | Isolated Intracranial (319) | P | |
|---|---|---|---|
| LKW-to-Alteplase Min, Median (IQR) | 120 (92–163) | 112 (83–156) | 0.323 |
| Intravenous Alteplase | 39 (65%) | 174 (55%) | 0.157 |
| LKW-Groin Min, Median (IQR) | 328 (197–425) | 267 (180–368) | 0.018 |
| Acute Treatment Approach | |||
| Cervical ICA Before Intracranial LVO | 34 (57%) | - | |
| Cervical ICA After Intracranial LVO | 8 (13%) | - | |
| No Cervical ICA Acute Treatment | 13 (22%) | - | |
| Cervical ICA Inaccessible | 5 (8%) | - | |
| Acute Treatment Type (N=42) | |||
| Cervical ICA stent | 34 (81%) | - | |
| Cervical ICA angioplasty alone | 8 (19%) | - | |
| Number EVT Passes, Median (IQR) | 2 (1–2) | 1 (1–1.5) | 0.087 |
| TICI 2b-3 | 35 (58%) | 263 (82%) | <0.0001 |
| ICH | 8 (13%) | 16 (5%) | 0.037 |
| Follow-Up Stent Patency (N=22) | 12 (55%) | - | - |
| 90-Day mRS 0–2 | 18 (34%) | 121 (43%) | 0.288 |
| 90-Day Mortality | 12 (23%) | 62 (22%) | 0.859 |