Table 1.
Clinicopathological characteristics of the IPMN Study Cohort
Total (n=15) | IPMN with low-grade dysplasia (n=3) | IPMN with moderate-grade dysplasia (n=2) | IPMN with high-grade dysplasia (n=7) | Carcinoma arising from IPMN (n=3) | |
---|---|---|---|---|---|
Median age (years) | 74 | 76 | 72 | 74 | 76 |
Gender (%) | |||||
Male | 9 (60) | 2 (66.7) | 1 (50) | 3 (42.9) | 3 (100) |
Female | 6 (40) | 1 (33.3) | 1 (50) | 4 (57.1) | 0 |
Clinical presentation (%) | |||||
Symptomatic | 9 (60) | 2 (66.7) | 1 (50) | 4 (57.1) | 2 (66.7) |
Incidental Finding | 6 (40) | 1 (33.3) | 1 (50) | 3 (42.9) | 1 (33.3) |
Location (%) | |||||
Head | 7 (43.8) | 0 | 1 (50) | 4 (50) | 2 (66.7) |
Uncinate process | 3 (18.8) | 1 (33.3) | 1 (50) | 1 (12.5) | 0 |
Body | 3 (18.8) | 1 (33.3) | 0 | 2 (25) | 0 |
Tail | 2 (12.5) | 1 (33.3) | 0 | 1 (12.5) | 0 |
Diffuse | 1 (6.2) | 0 | 0 | 0 | 1 (33.3) |
Biliary stent (%) | |||||
Yes | 1 (6.7) | 0 | 0 | 0 | 1 (33.3) |
No | 14 (93.3) | 3 (100) | 2 (100) | 7 (100) | 2 (66.7) |
Median CA 19–9 (U/mL) | 18.1 | 18.2 | 42.3 | 15.1 | 24.3 |
Post-op tumor size (%) | |||||
<3 cm | 14 (87.5) | 2 (66.7) | 2 (100) | 7 (87.5) | 3 (100) |
≥3 cm | 2 (12.5) | 1 (33.3) | 0 | 1 (12.5) | 0 |
Tumor stage (%) | |||||
Tis | 5 (31.3) | 0 | 0 | 5 (62.5) | 0 |
T1 | 2 (12.5) | 0 | 1 (50) | 0 | 1 (33.3) |
T2 | 1 (6.2) | 0 | 0 | 0 | 1 (33.3) |
T3 | 1 (6.2) | 0 | 0 | 0 | 1 (33.3) |
Unspecified | 7 (43.8) | 3 (100) | 1 (50) | 3 (37.5) | 0 |
Lymph node metastasis (%) | |||||
N0 | 9 (56.2) | 0 | 1 (50) | 5 (62.5) | 3 (100) |
Unspecified | 7 (43.8) | 3 (100) | 1 (50) | 3 (37.5) | 0 |
Duct involvement | |||||
Main duct | 4 (25) | 1 (33.3) | 1 (50) | 2 (25) | 0 |
Branch ducts | 1 (6.2) | 0 | 0 | 1 (12.5) | 0 |
Mixed | 3 (18.8) | 0 | 1 (50) | 2 (25) | 0 |
None | 4 (25) | 1 (33.3) | 0 | 2 (25) | 1 (33.3) |
Unspecified | 4 (25) | 1 (33.3) | 0 | 1 (12.5) | 2 (66.7) |
Subtype | |||||
Pancreatobiliary | 6 (37.5) | 2 (66.7) | 1 (50) | 2 (25) | 1 (33.3) |
Intestinal | 2 (12.5) | 0 | 0 | 1 (12.5) | 1 (33.3) |
Foveolar/Intestinal | 1 (6.2) | 0 | 0 | 1 (12.5) | 0 |
Intestinal/Pancreatobiliary | 1 (6.2) | 0 | 0 | 1 (12.5) | 0 |
Intestinal/Gastric | 1 (6.2) | 0 | 0 | 1 (12.5) | 0 |
Gastric/Pancreatobiliary | 1 (6.2) | 0 | 1 (50) | 0 | 0 |
Unspecified | 4 (25) | 1 (33.3) | 0 | 2 (25) | 1 (33.3) |