TABLE 1.

Demographic characteristics of temporal bones used and qualitative immunoreactive macrophage presence

HTB	Side	Age	Yr With CI	Macrophage Localization	Iba1	CD68	Histopathology
1-CI	Left	89	16	Around CI, SV, SG, MM	+++	+++	Translocation and lateral wall. Cochleostomy Fibrosis, mild hydrops
1-CI	Right	89	18	Around CI SV, SG, MM	+++	+++	Translocation, cochleostomy. Fibrosis, Stria atrophy
2-NI	Left	61	NA	SV, SG, MM	++	++	Mild hydrops
2-CI	Right	61	1	Around CI	++	++	Translocation, no cochleostomy. Fibrosis, hydrops
3-NI	Left	87	NA	SV, SG, MM	+	+	Normal
3-CI	Right	87	19	SV, SG, MM	+	+	Translocation, cochleostomy. Fibrosis, strial atrophy, hydrops
4-NI	Left	65	NA	Minimum SV, SG, MM	+	+	Normal
4-CI	Right	65	2	Minimum SV, SG, MM	+	+	No translocation, cochleostomy. Fibrosis. Hydrops with rupture
5-CI	Left	92	11	Minimum	+	+	No translocation no cochleostomy. Mild fibrosis
5-NI	Right	92	NA	Minimum	+	+	Stria atrophy
6-CI	Left	75	10	Around CI, SV, SG, MM	+++	+++	Translocation, cochleostomy. Fibrosis, mild hydrops
6-NI	Right	75	NA	SV, SG, MM	+	+	Strial atrophy
7-CI	Left	73	3	Around CI, SV, SG, MM	+++	+++	Translocation and lateral wall, cochleostomy fibrosis, atrophy.
7-NI	Right	73	NA	Minimum	+	+	Stria atrophy
8-CI	Left	87	10	SV, SG, MM	+++	+++	Translocation, cochleostomy, fibrosis. Ossified, hydrops
8-NI	Right	87	NA	SV, SG, MM	+	+	Normal
HTB: Normal controls with normal hearing
9-C	Left	26	NA	SV, SG, MM	++	++	Normal
10-C	Left	38	NA	SV, SG, MM	++	++	Normal
11-C	Right	50	NA	SV, SG, MM	++	++	Normal

HTB 1 had bilateral CI and HTBs 2 to 8 had unilateral CI and contralateral nonimplanted side (NI). HTBs 9 to 11 are from normal hearing (C).

C indicates controls with normal hearing; CI, cochlear implant; HTB, human temporal bone; MM, mid-modiolus; NA, not applicable; NI, nonimplanted contralateral side; SG, spiral ganglia; SV, stria vascularis.

Qualitative presence: +: minimum, ++: medium, +++ strong.