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. Author manuscript; available in PMC: 2021 Jul 4.
Published in final edited form as: Nat Immunol. 2021 Jan 4;22(2):193–204. doi: 10.1038/s41590-020-00829-6

Extended Data Fig. 5. NIK-mediated stimulation of antitumor T cell responses requires HK2.

Extended Data Fig. 5

Flow cytometric analysis of the frequency and absolute cell number of CD4 and CD8 T cells (a), PD1+Tim3+ CD8 T cells (b) and flow cytometric analysis of the expression level (MFI) of PD1 and Tim3 in CD8 T cells (c) in day-27 tumor of wildtype (WT), NIKiTg (iTg), NIKiTgHk2iKO (iTg-iKO) mice injected s.c. with 5 x 105/mouse MC38 colon cancer cells (a,b, WT: n=4; iTg: n=4; iTg-iKO: n=3). Data are representative of two independent experiments. Summary data are shown as mean ± s.e.m. with P values were determined by two-tailed Student’s t test.