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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Drug Discov Today. 2020 Oct 20;26(1):31–43. doi: 10.1016/j.drudis.2020.10.011

TABLE 1.

Examples of antimicrobial resistance mechanisms in MRSA

Resistance mechanism Antimicrobial agents
Limiting drug uptake Glycopeptides
Modification of drug target β-lactams; glycopeptides; lipopeptides; aminoglycosides; tetracyclines; macrolides; lincosamides; oxazolidinones; streptogramins; fluoroquinolones; metabolic pathway inhibitors
Inactivation of drug β-lactams; chloramphenicol
Active drug efflux Tetracyclines