Association between proportional performance of the ABCDEF bundle and patient outcomes. Adjusted hazard ratio and 95% confidence interval for ICU discharge, hospital discharge, and death, comparing patients with a given proportion of eligible ABCDEF bundle elements performed on a given day with patients with none of the bundle elements performed that day. Hazard ratios are adjusted for baseline, ICU admission characteristics, and daily covariates, measured the same day as bundle performance. ICU, intensive care unit. Reproduced with permission from Pun et al.22