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Genomic analyses: A. Copy number breaks (CNBs) determined from exome sequencing data in n=211 patients. CDK12 biallelic mutation cases (n=23) in red, monoallelic cases (n=3) in yellow, and cancers with no CDK12 alterations (controls) in blue. The black line indicates the median number of CNBs (median =513) in the whole cohort.
B. Violin plot depicting CNB numbers in CDK12 mutated in red and controls in blue.
