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. Author manuscript; available in PMC: 2021 May 30.
Published in final edited form as: Nat Chem Biol. 2020 Nov 30;17(2):213–221. doi: 10.1038/s41589-020-00656-8

Extended Data Fig. 1. Activity of PolD and PolK with 5’-OAP.

Extended Data Fig. 1

Shown are HPLC chromatograms at 260 nm for a full reaction with PolK, a full reaction with PolD, a control without enzyme, and a control without α-KG. No consumption of 5’-OAP was detected. The results were reproducible in at least two independent assays.