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Internally responsive activatable multimodal imaging. a) Multimodal imaging combines advantages and disadvantages of various anatomical and molecular imaging modalities. FL refers to fluorescence imaging. b) Internally responsive multimodal imaging nanomaterials are activated by pH gradients, redox potential, enzymes, or combinations of these. NP, GSH, and ROS refer to nanoparticle, glutathione, and reactive oxygen species, respectively.
