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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Adv Healthc Mater. 2020 Jul 21;10(5):e2000690. doi: 10.1002/adhm.202000690

Figure 4.

Figure 4.

pH-activatable multimodal imaging incorporating an acid liable group. a) In slightly acidic conditions, FL and MR activation of the nanoprobes occurred after releasing a FeIII-containing moiety. b,c) The release of the FeIII-containing moiety could be monitored in vivo by the ratio of the emissions at 475 and 800 nm (I475/I800). d) T1-weighted MR images and e) corresponding analysis. In (b)–(e), probe was the pH-activatable nanoprobe and UCNP-GA was a nonresponsive control for comparison. Reproduced with permission.[34] Copyright 2019, Wiley.