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Projected change in Lyme disease cases by region for 2040 – 2050 and 2090 – 2100 under the a) upper (RCP8.5) and b) moderate (RCP4.5) climate change scenarios. Case changes refer to raw case counts rather than incidence and indicate the average change in cases for a particular decade relative to hindcasted values for 2010 – 2020. Bars represent 95% prediction intervals. Regions are defined in Fig. 1.
