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. Author manuscript; available in PMC: 2021 Jul 4.
Published in final edited form as: Nat Struct Mol Biol. 2021 Jan 4;28(1):92–102. doi: 10.1038/s41594-020-00534-w

Extended Data Fig. 4: Intramolecular crosslinks within Ski8 validate the XL-MS results.

Extended Data Fig. 4:

a, Ski8 intramolecular crosslinks modeled on the structure of Ski8. The histogram shows the frequency of XL-MS events as a function of distance between the α-carbons (Cα) of the crosslinked lysines (red spheres). The crosslinkable limit of DSS is 27.4 Å. b, Ski8 intramolecular crosslinks modeled on the core complex show that the crosslinked residues are away from the interaction surface with Spo11.