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. Author manuscript; available in PMC: 2021 Jul 4.
Published in final edited form as: Nat Struct Mol Biol. 2021 Jan 4;28(1):92–102. doi: 10.1038/s41594-020-00534-w

Fig. 3: DNA-binding by the core complex analyzed by AFM.

Fig. 3:

a. Wide-field views of core complexes bound to pUC19 plasmids.

b. Examples of binding to ends (1-end), internally on duplex DNA (duplex), junctions of three DNA arms (3-way), and junctions with four DNA arms (4-way).

c. Quantification of DNA-bound particles with the three substrates assayed. SC, supercoiled.

d. Fractions of duplex-bound particles that exhibited DNA bending.

e. Histogram of bending angles (n = 212 particles). Angles at randomly chosen positions along the DNA are shown as a control (n = 115 particles).

P values in c, d are from two-sided Fisher’s exact tests.

Data for graphs in c, d, e are provided as Source Data.