Table 3.
Evidence supporting the kidney as a reservoir for HIV-1.
Findings | References |
---|---|
Detection of HIV-1 nucleic acids in renal biopsies of patients with HIVAN | [3, 4, 9, 81–83] |
Phylogenetic analysis of HIV-1 sequences in kidney biopsies of patients with HIVAN | [4] |
HIV-1 shedding and sequence compartmentalization in urine of PLWH | [46, 84] |
Infection of HIV-1 negative allograft kidneys in PLWH undergoing kidney transplantation | [5] |
Detection of donor and recipient HIV-1 strains in urine, renal epithelial cells and allograft kidney biopsy following HIV+ to HIV+ kidney transplantation | [18] |