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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Cardiovasc Toxicol. 2020 Oct 12;21(2):169–178. doi: 10.1007/s12012-020-09610-5

Table 2:

Comparison of creatinine-normalized urinary biomarkers (median [interquartile range]) among participants dichotomized into high and low atrial and atrioventricular conduction parameters.

All patients PR interval P wave duration PR segment
≤ 163.32 ms > 163.33 ms p value ≤ 104.73 ms > 104.74 ms p value ≤ 55.20 ms > 55.21 ms p value
Cotinine (μg/g) 23.1 [1.6 – 794.1] 30.6 [1.5 – 948.4] 23.0 [1.8 – 647.7] 0.45 238.3 [2.3 – 102.5] 5.8 [1.4 – 627.1] 0.08 130.7 [2.4 – 1070.1] 9.5 [1.2 – 591.3] 0.03
Dopamine (μg/g) 165.4 [127.6 – 214.1] 179.8 [142.3 – 228.5] 150.6 [119.7 – 189.5] 0.01 180.1 [142.0 – 234.7] 111.6 [180.3 – 168.8] 0.01 168.8 [140.7 – 219.8] 160.5 [119.7 – 204.9] 0.07
Epinephrine (μg/g) 4.7 [2.4 – 7.9] 5.6 [2.9 – 8.6] 8.6 [4.1 – 7.5] 0.23 5.9 [3.5 – 9.8] 3.9 [1.7 – 6.4] 0.01 5.2 [2.1 – 8.9] 4.2 [2.5 – 7.5] 0.75
Norepinephrine (μg/g) 37.2 [26.0 – 53.3] 36.7 [26.9 – 52.6] 38.0 [22.9 – 56.4] 0.86 41.2 [30.7 – 54.5] 31.9 [22.1 – 52.3] 0.03 36.4 [28.0 – 51.7] 37.5 [22.7 – 55.6] 0.75