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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Hypertension. 2020 Nov 30;77(2):420–431. doi: 10.1161/HYPERTENSIONAHA.120.15793

Figure 4: Drinking responses to 0.3M and 0.45M saline.

Figure 4:

Control and mice subjected to DOCA with concomitant intracerebroventricular infusions of either artificial cerebrospinal fluid (aCSF), TRV027, or losartan (LOS) were presented with a choice of tap water vs 0.30M saline (A) or with a choice of tap water vs 0.45M saline (B). Total water intake, total saline intake, total fluid intake (calculated as total water intake plus total saline intake), and percentage of total fluid intake from saline (calculated as total saline intake/total fluid intake x 100), are shown. All data are expressed as mean±SEM. Data were analyzed by one-way ANOVA with Tukey’s multiple comparisons procedure. *p<0.05 and **p<0.0001 compared with aCSF; #p<0.05 and ##p<0.0001 compared with DOCA+aCSF. N values are: 0.30M saline: aCSF (n=16), DOCA+aCSF (n= 16), DOCA+TRV027 (n=18), DOCA+losartan (n=17). 0.45M saline: aCSF (n=11), DOCA+aCSF (n= 11), DOCA+TRV027 (n=14), DOCA+losartan (n=12).