Figure 5.

NFT densities were positively associated with activated microglia densities in gray matter and white matter of PPA‐AD. (A) There was a positive relationship between NFT densities and activated hypertrophic microglia densities (P < 0.01), as displayed by the predicted line (slope: 0.25) from the mixed model. Data displayed include all 5 participants with 14 observations each (five language and two non‐language regions per hemisphere). (B) There was a positive relationship between NFT densities and optical densities of white matter activated microglia (P < 0.01), as illustrated by the predicted line (slope: 18 212). Data displayed include all five participants with eight observations each (two language and two non‐language regions per hemisphere). When creating the predicted lines, we used the left hemisphere, language regions, and the medians for age at death (64) and postmortem interval (14) for the adjusting variables.