(A) Fasting blood glucose and (B) Plasma insulin levels measured post 15 weeks of respective diet feeding. Blood glucose was measured using commercial finger-stick glucose meter and plasma insulin was measured using ultra-sensitive mouse insulin ELIZA kit. (n=5-8 per group); CD, Control diet; HFD, High fat diet; DOX, Doxycycline; SOLA, 20-HETE antagonist; **P<0.01, ***p<0.001, ****p<0.0001 based on two-way ANOVA with post-hoc Tukey’s test.