Recovery from jetlag is accelerated in both Avpcre/+ and Avpcre/cre mice. A. Representative double-plotted wheel-running actograms illustrating re-entrainment following the 6 h shift in the light:dark cycle. Lighting conditions before and after the 6 h shift are illustrated with internal shading and light:dark bar above and below each actogram, respectively (black/gray = darkness, white = light). B. Avpcre/+ and Avpcre/cre mice re-entrain faster than Avp+/+ mice (Genotype: F (2,63) = 16.7. p < 0.001, ηp2 = 0.36, Sex: F (1,63) = 5.95, p < 0.05, ηp2 = 0.09, Genotype*Sex: F (2,63) = 0.5, p > 0.6, ηp2 = 0.02). Numbers below abscissa represent sample size for each genotype, collapsed across sex (9-12/sex). Post hoc LSM Contrasts: * Differs from Avp+/+, genotype difference collapsed across sex, p < 0.05, ✢ Sex difference divided by genotype, p < 0.05. Other conventions as in Figure 1.