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. 2021 Jan 20;8:599044. doi: 10.3389/fped.2020.599044

Figure 4.

Figure 4

Effects of genetic polymorphisms on the C0/D ratio in different pediatric patient groups: (A–C) wild-type and mutant genotypes for UGT2B7 211G>T rs1057910, (D–F) UGT2B7 802T>C rs12233719, (G–I) UGT2B7 161C>T rs7439366, (J–L) UGT2B7 125T>C rs7668258, and (M–O) CYP2C9*3 1075A>C rs7668282. Here, (A,D,G,J,M) show data from the total of 194 patients who were administered the VPA oral solution or SR tablets; (B,E,H,K,N) show the data from 135 patients who were administered the VPA oral solution; and (C,F,I,L,O) show data from 59 patients who were administered the VPA SR tablets.