TABLE 1.

Investigational compounds and concentrations in the current study.

Compound	IC50 ROCK1	IC50 ROCK2	Concentration	Selectivity
Compound 31	2.9 ± 0.5 nM	4 ± 0.6 nM	0.01, 0.1 and 1 μM	ROCK1 and 2
Compound A11	341.1 ± 38 nM	6.1 ± 1.4 nM	0.1, 1 and 10 μM	ROCK2 selective