Table 2.
The association of clinical pathological variables with the pCR and NAC efficiency using univariate logistic analysis.
| Variables | Non-pCR (n = 138) | pCR (n = 57) | P-value (Non-Pcr vs. pCR) | ORR (n = 168) | NR (n = 27) | P-value (ORR vs. NR) |
|---|---|---|---|---|---|---|
| Age(year) | 0.881 | 0.403 | ||||
| ≤50years | 71 | 30 | 85 | 16 | ||
| >50years | 67 | 27 | 83 | 11 | ||
| Menopausal state | 0.535 | 0.857 | ||||
| Not menopause | 88 | 39 | 109 | 18 | ||
| Menopause | 50 | 18 | 59 | 9 | ||
| Tumor stage (cT) | 0.002 | <0.001 | ||||
| cT1 | 6 | 6 | 6 | 6 | ||
| cT2 | 90 | 47 | 127 | 10 | ||
| cT3 | 36 | 4 | 31 | 9 | ||
| cT4 | 6 | 0 | 4 | 2 | ||
| Ki-67 staining | 0.108 | 1.0 | ||||
| <20% | 7 | 0 | 6 | 1 | ||
| ≥20% | 131 | 57 | 162 | 26 | ||
| P53 expression | 0.384 | 0.445 | ||||
| − | 42 | 21 | 56 | 7 | ||
| + | 96 | 36 | 112 | 20 | ||
| CK5/6 expression | 0.133 | 0.961 | ||||
| − | 36 | 21 | 49 | 8 | ||
| + | 102 | 36 | 119 | 19 | ||
| EGFR expression | 0.885 | 0.115 | ||||
| − | 18 | 7 | 19 | 6 | ||
| + | 120 | 50 | 149 | 21 | ||
| Classification | 0.661 | 0.617 | ||||
| NBLBC | 15 | 5 | 16 | 4 | ||
| BLBC | 123 | 52 | 152 | 23 |
NAC, neoadjuvant chemotherapy; NBLBC, non-basal-like breast cancer; BLBC, basal-like breast cancer; ORR, overall response group; NR, no response group.