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The relationship between changes of biomarkers and the efficacy of chemotherapy.
| Variables | Grouping | Chemotherapy effect | p-value | |
|---|---|---|---|---|
| ORR | NR | |||
| CK5/6 | Pos→Neg. | 15 | 3 | 0.676 |
| Neg.→Pos. | 10 | 3 | ||
| EGFR | Pos→Neg. | 12 | 2 | 0.602 |
| Neg.→Pos. | 6 | 2 | ||
EGFR, epidermal growth factor receptor; CK5/6, cytokeratin5/6; ORR, overall response group; NR, no response group; Neg., Negative; Pos., Positive.
