Table 3.
Adjusted relative risk (RR) and 95% confidence interval (CI) for ASD (n = 57) versus TD (n = 116) in association with prenatal maternal PFAS concentrations and principal component scores.
| PFAS (ng/mL) a or principal component score |
Log 2-transformed PFAS RR b (95% CI) |
Untransformed PFAS RR b (95% CI) |
|---|---|---|
| PFOA | 1.20 (0.90, 1.61) | 1.31 (1.04, 1.65) |
| PFOS | 0.97 (0.74, 1.28) | 0.99 (0.90, 1.08) |
| PFHxS | 0.88 (0.77, 1.01) | 0.90 (0.54, 1.51) |
| PFNA | 1.24 (0.91, 1.69) | 1.79 (1.13, 2.85) |
| PC-1 c | 1.03 (0.87, 1.22) | 1.10 (0.97, 1.25) |
a
Four PFAS detected in more than 99% of the study samples were individually included in the Poisson regression model.
b
Adjusted for child’s sex and birth year, homeownership, maternal education, and maternal vitamin intake in the first month of pregnancy.
c
Selected from the principal component analysis because its eigenvalue was higher than 1.