Table 1.
HRT | LRT | Main effects | Interaction | ||||||
---|---|---|---|---|---|---|---|---|---|
Before IF | During IF | Before IF | During IF | Time | HRT vs LRT | Time vs Line | |||
Fed | Fasted | Fed | Fasted | ||||||
Body weight (g) | 252.4 (13.5) | 232.1 (7.0) | 209.0 (7.1) | 308.7 (16.8) | 279.3 (11.2) | 253.5 (10.6) | 23.38(14,140)p<0.001 | 5.49 (1,10)p=0.041 | 0.51(14,140) p=0.932 |
Fat mass (g) | 50.9 (10.5) | 28.3 (3.3) | 23.4 (3.5) | 79.7 (7.3) | 51.6 (5.9) | 45.7 (5.1) | 16.17(14,140) p<0.001 | 5.23(1,10) p=0.044 | 0.19(14,140) p=0.999 |
Lean mass (g) | 173.3 (4.1) | 171.9 (5.5) | 159.7 (5.1) | 198.0 (11.7) | 193.7 (9.3) | 177.3 (8/9) | 12.70(14,140) p<0.001 | 2.02(1,10) p=0.185 | 0.19(14,140) p=0.783 |
Food intake (g) | 10.9 (0.4) | 18.7 (0.6) | 0 | 11.6 (0.4) | 19.7 (0.7) | 0 | 79.66(98,1274) p<0.001 | 0.874(1,13) p=0.367 | 0.60(98,1274) p=0.999 |
Water intake (ml) | 26.4 (1.7) | 43.2 (2.7) | 9.4 (2.7) | 20.0 (0.7) | 36.5 (1.2) | 6.0 (0.8) | 575.07(98,1372) p<0.001 | 10.27(1,14) p=0.006 | 1.10(98,1372) p=0.249 |
Physical Activity | |||||||||
Distance traveled (cm/min) | 8.6 (0.6) | 12.2 (1.6) | 7.6 (0.5) | 8.8 (0.8) | 15.3 (3.2) | 7.8 (1.0) | 8.29(98,1274) p<0.001 | 0.51(1,13) p=0.486 | 0.92(98,1274) p=0.697 |
Time spent resting (sec/min) | 52.7 (0.3) | 52.3 90.5) | 54.4 (0.2) | 53.5 (0.3) | 52.4 (0.6) | 54.6 (0.4) | 16.79(98,1372) p<0.001 | 0.32(1,14) p=0.583 | 0.93(98,1372) p=0.679 |
Horizontal counts (per min) | 13.5 (0.8) | 15.4 (1.4) | 10.4 (0.6) | 12.8 (1.0) | 17.6 (3.0) | 10.5 (1.1) | 9.14(98,1274) p<0.001 | 0.11(1,13) p=0.748 | 0.78(98,1274) p=0.544 |
Ambulatory counts (per min) | 5.1 (0.4) | 7.2 (0.9) | 4.3 (0.3) | 5.5 (0.6) | 9.6 (2.2) | 4.8 (0.7) | 5.18(98,1274) p<0.001 | 0.77(1,13) p=0.398 | 0.92(98,1274) p=0.686 |
Vertical counts (per min) | 0.32 (0.04) | 0.69 (0.19) | 0.48 (0.06) | 0.44 (0.06) | 0.74 (0.09) | 0.64 (0.25) | 6.09(98,1274) p<0.001 | 0.34(1,12) p=0.574 | 1.07(98,1176) p=.0304 |
For body weight, fat and lean mass: baseline values immediately before start of IF; fed-day is after 9 weeks of IF, and fasted day is after 10 weeks of IF. Food, water, and activity through 11 weeks of IF; For activity, 17 days of baseline activity before onset of IF calculated. Main effect of time includes all measurements before and after IF without differentiating between fed and fasted days.