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. Author manuscript; available in PMC: 2022 Jan 19.
Published in final edited form as: Circulation. 2020 Dec 3;143(3):244–253. doi: 10.1161/CIRCULATIONAHA.120.048026

Table 1.

Age and Gender Adjusted Associations of Social Determinants of Health with Fatal Incident Coronary Heart Disease and Incident Nonfatal Myocardial Infarction

Healthy People 2020 Domain Social Determinants of Health  Incident Fatal CHD Incident Nonfatal MI
HR
(95% CI)
p HR
(95% CI)
p
Social and community context Black race 1.65
(1.37, 1.98)
<0.001 0.95
(0.83, 1.09)
0.463
Social isolation (Saw no friends/family in the past month) 1.38
(0.95, 2.01)
0.093 1.09
(0.81, 1.46)
0.587
Social isolation (Do not have anyone to care for you if you become ill or disabled) 0.94
(0.71, 1.25)
0.674 1.00
(0.82, 1.22)
0.982
Education Low education (< High school) 2.10
(1.67, 2.63)
<0.001 1.43
(1.19, 1.73)
0.0002
Economic stability Low annual household income (<$35,000) 1.91
(1.55, 2.36)
<0.001 1.32
(1.15, 1.53)
0.0001
Neighborhood/ built environment Zip code with high poverty (>25% residents living below Federal poverty line) 1.34
(1.08, 1.66)
0.009 1.00
(0.84, 1.18)
0.971
Health and healthcare Residence in a Health Professional Shortage Area 1.08
(0.90, 1.30)
0.405 0.93
(0.81, 1.06)
0.206
Residence in a State with least public health infrastructure* 1.21
(1.00, 1.55)
0.005 1.06
(0.93, 1.21)
0.398
Lack of health insurance 1.41
(0.94, 2.13)
0.100 1.35
(1.04, 1.76)
0.026
*

Public Health Infrastructure is calculated based on America’s Health Ranking data; see text.

Bolded SDOH had associations with p<0.10.