Table 3.

Number of Social Determinants of Health and Associations with Fatal Incident Coronary Heart Disease and Incident Nonfatal Myocardial Infarction

Fatal Incident CHD				Incident Nonfatal MI
Number of SDH ^†	Number of events	HR (95% CI)		Number of SDH ^††	Number of events	HR (95% CI)
Number of SDH ^†	Number of events	Crude	Fully adjusted ^*	Number of SDH ^††	Number of events	Crude	Fully adjusted ^*
0	55	1.00 (reference)	1.00 (reference)	0	390	1.00 (reference)	1.00 (reference)
1	97	1.24 (0.90, 1.71)	1.00 (0.72, 1.38)	1	310	1.32 (1.14, 1.53)	1.02 (0.87, 1.20)
2	105	1.96 (1.43, 2.68)	1.25 (0.91, 1.74)	≥2	128	1.57 (1.30, 1.90)	1.14 (0.93, 1.41)
≥3	154	2.78 (2.07, 3.74)	1.50 (1.09, 2.06)

p for trend		<0.0001	<0.0001			<0.0001	0.26

Adjusted for sociodemographic factors, medical conditions, use of medications, functional status, health behaviors, and physiologic variables

^†

SDOH included Black race, low education, low annual household income, zip code with high poverty, residence in the worst ranked states for public health infrastructure, lack of health insurance, social isolation (saw no friends/family in the past month). Note that not all available events are included in this table due to missing data on SDH; all events were used in modeling with multiple imputation.

^††

SDOH included low education, low annual household income and lack of health insurance

CHD = coronary heart disease. CI = confidence interval. HR = hazard ratio. MI = myocardial infarction. SDH = social determinants of health