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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Semin Perinatol. 2020 Dec 1;45(1):151356. doi: 10.1016/j.semperi.2020.151356

Fig, 2. Digital microfluidics (DMF) method.

Fig, 2.

(A) The prototype point-of-care device is designed on a DMF platform; (B) DMF is based on electric fields to manipulate droplets of blood or “electrowetting”; and (C) Disposable “chip” cartridge is tightly regulated at 37°C and contains all the required reagents in dried form, which are then reconstituted once sample analysis is initiated. The assay requires ~50 μL of whole blood.