TABLE 2.
Perioperative outcomes of patients with preoperatively diagnosed duodenal adenomas stratified by final pathology
| Benign n = 32 (71) |
Malignant n = 13 (29) |
p value | |
|---|---|---|---|
| Age at surgery (years) | 59 (41–80) | 68 (50–89) | < 0.05 |
| Female | 19 (59) | 6 (46) | 0.42 |
| Race | |||
| Caucasian/White | 20 (63) | 12 (92) | < 0.05 |
| African-American/Black | 12 (37) | 1 (8) | < 0.05 |
| Body mass index (kg/m2) | 28.3 (17.9–44.7) | 26.6 (18.4–37.1) | 0.83 |
| Alcohol use within the last 5 yearsa | 2 (6) | 3 (23) | 0.10 |
| Tobacco use within the last 5 yearsb | 5 (16) | 2 (15) | 0.98 |
| Age-adjusted Charlson index | 2 (0–7) | 4 (1–7) | 0.05 |
| Preoperative biliary stent | 3 (9) | 6 (46) | < 0.01 |
| Asymptomatic at diagnosis | 12 (38) | 2 (15) | 0.15 |
| High-grade dysplasia on biopsy | 7 (22) | 5 (38) | 0.25 |
| Tumor size (mm) | 35 (4–100) | 25 (10–50) | < 0.05 |
| Pancreatic duct (mm) | 2.71 (± 0.97) | 2.85 (± 0.80) | 0.66 |
| Bile duct (mm) | 7.52 (± 3.19) | 12.31 (± 4.64) | < 0.01 |
| Estimated blood loss (ml) | 100 (20–700) | 200 (25–600) | 0.78 |
| Length of surgery (min) | 193 (109–480) | 172 (125–397) | 0.18 |
| Major complicationsc | 14 (44) | 0 (0) | < 0.01 |
| Postoperative pancreatic fistula | 7 (22) | 1 (8) | 0.26 |
| Grade C | 4 (13) | 0 (0) | 0.18 |
| Length of stay (days) | 9 (2–90) | 7 (5–12) | < 0.05 |
| Readmission | 6 (19) | 2 (15) | 0.79 |
| Patient death | 3 (9) | 0 (0) | 0.36 |
Continuous variables are expressed as median (range); categorical variables are expressed as n (%) Bold values denote p values < 0.05
a
Alcohol use is defined as > 3 drinks/day or > 7 drinks/week for women and > 4 drinks/day or > 14 drinks/week for men (National Institute on Alcohol Abuse and Alcoholism)
b
Tobacco use is defined as daily use of any tobacco product (Substance Abuse and Mental Health Services Administration)
c
Major complications (Clavien–Dindo grade ≥ III)