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Association of CHK1 gene abundances with cancer-related biological pathways. (A) GSEA of hallmark pathways including immune-related prexasertib resistance signature, associated with CHK1-lo and CHK1-hi gene expression in the TCGA cohort. (B) Enrichment plot of E2F targets and immune-related prexasertib resistance signature in TCGA CHK1-hi and -lo groups. (C) The interactions of the genes in the immune-related prexasertib resistance signature as clustered by the STRING database.
