Table 1.
Medication | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 |
---|---|---|---|---|---|
Randomization | |||||
Buprenorphine | 2+2+2 mg +(2hs) | ||||
Lorcaserin or Placebo | 1 mg (b.i.d) or matched placebo | ||||
Naltrexone | 1+3 mg | 12.5 mg | 25 mg+ XR-Naltrexone 380mg i.m. | ||
Ancillary Medications | clonidine [Maximum Daily Dose (MDD) = 0.3mg], prochlorperazine (MDD= 30mg), clonazepam (MDD= 1.5mg), and zolpidem (MDD=10mg) were prescribed. |