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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Expert Opin Ther Targets. 2020 Nov 23;25(1):63–73. doi: 10.1080/14728222.2021.1849145

Figure 2: Interplay of integrin, YAP/TAZ, and STAT3 mediated mechanosensing to modulate ECM production, integrin production, and cell morphology and growth.

Figure 2:

Abbreviations: ECM – Extracellular matrix; FAK – Focal adhesion kinase; STAT3 – Signal Transducer and Activator of Transcription 3; ROCK – Rho associated protein kinase; MRTF – Myocardin-related transcription factor; SRF – Serum response factor. Star indicates transcription factors. Rhombus indicates kinases. Ovals indicate other factors (e.g. cytokines, enzymes, proteins, etc.).